On the fly, as in during the mash? No, none that I know of.
But if you've been using a calculator and all the minerals and grains were already entered into the calculator already, and you notice a 0.3pH difference, from predicted, by all means add some acid or alkali in the calculator, to correct the prediction, and add that amount to your mash. Just realize, the mash progresses rather fast, by the time you've re-calculated and added your acid (or alkali), most of the mash has probably converted already.
The water gurus recommend taking the mash pH reading at the end of the mash. As all chemistry and reactions have stabilized by then and become more predictable. You would use that reading as your reference of mash pH. Then in your next brew, if needed, correct accordingly and measure again, at the end, and compare the values.
Don't forget you should always measure mash pH at or very close to your meter's calibration temp. Or at least at room temps if it has ATC (Automatic Temperature Correction) built in. That's important, and the way most, if not all mash calculators are constructed. You can cool a (small, 0.5-1 oz) sample quickly by scooping some mash out (from the center) and pouring it into a glass or cup that's been frozen.
Really, download a (free) copy of Bru'nWater and things may become a lot clearer. There are tons of instructions and educational notes included, right on the spreadsheet.