tl;dr: refract goes in the trash. use precision hydrometers and just deal with (gross up main batch) losing 150mL per sample.
I have lab grade precision hydrometers, and both optical and digital Brix refractometers.
When i was testing the refractometers against each other they were always exactly in agreement with each other.
The precision hydrometers are exactly that - precise. There are 3... FG=0-8.5P, Mid Range=8P-16.5P and High=16P-24.5P. I made reference solutions of sucrose at their crossover points (8P and 16P), and also checked the low one against pure water (0P) and the high one against high gravity (24P). All measured exactly spot on. I even cooled samples to check how they responded to temperature, and again, they matches *exactly* with what the correction chart said. Best value in brewing tools I've ever purchased. The standard 0.002 increment hydrometers you get for $7 for the LHBS are not precise or accurate enough to be used in conjunction with a refractometer.
On pre-boil wort there is a ~1.015-1.025 multiplier needed to convert from Brix to Plato. Every beer yields a unique conversion factor. So a measurement of 13.2 Plato would give something like 13.4 Brix. For the refract it's critical to to take measurements using clear, bubble free wort AND with wort that is the same temperature as the instrument.
Once fermentation starts you might as well put away the refract unless it's an exact rebrew where you have previous data points (and i mean exact... same recipe, same actual OG, etc). Every calculator i've ever used where i have the correction factor, along with refract and hydrometer measurements, never agree. Sometimes they are close, but sometimes they are off by A LOT. Just this past week i had one that was off by 1.5P. The refract said the beer was 1.018 (ready to rack)... so i did. But once i racked and checked a sample with the precision hydrometer it was 1.024! Hoping that doesn't come back to haunt me.