I cold crash with my Speidel sealed. This was after many times of doing a graduated crash over the span of a couple of days with the airlock still in place. Now, I use a spare Speidel cap that I drilled out and added a bulkhead with a ball lock gas-in post. I usually (unscientifically) put the cap on at the very tail end of fermentation to build a little positive pressure. Before I crash, I'll make sure the cap and collar nuts are tight, crank it down to 35 degrees and let it go. You'll see a little bit inward caving on the top of the unit around the large collar, but that's all I've ever experienced. No leaks from the valve or oxygenated beer.
I do a closed loop transfer to a keg that has about 3 psi in it. I'll connect the keg gas in post first, then to the Speidel and the suction will immediately pull the co2 in, providing enough pressure to blast any gunk out of the valve once I open it. This goes in to a cup and once it runs clear, I close the valve, attach my line from the valve to liquid out on the keg and open the valve back up to start the flow.
I've also accidentally pressured the Speidel to about 15psi once. It happened very fast and I could actually see it expanding. It held for the five or so seconds it took for me to pull the disconnect and depress the poppet.