Oh absolutely. Hefeweizen is the one strain I can’t really find a second style to use it for. Its really a one trick pony. I don’t do Saison or anything Belgian.Well call me crazy, but I'm not going to rack an IPA onto a Hefeweizen yeast cake or a porter onto Saison yeast.
But yeah, I did just split a 1056 into 2 starters. Well first, I had to do a starter because the pack was out of date. Second I plan to make 6 beers out of it. All 3 gallon batches. So far I’ve made an Irish Red followed by 2 stouts. The other starter I split off is going into a Centennial Blonde followed by a pale ale then an IPA. So yeah, I didn’t want the dark grains from the stout in the American beers and I didn’t want the hops from the American beers in the Irish Red or the stouts. Stuff like this is understandable. But I don’t usually make 6 beers out of 1 yeast.
Since I’m also doing 3 gallon batches, I rarely do a starter unless the pack is out of date or something.