You could, but time will do the same thing as stuff settles out. How much time will depend on some different things, OG, mash procedure, yeast strain, water chemistry and so on...
But there is gelatin for those of us who have little time, and even less patience.
You're not going to ruin your beer if that is what your asking. Well, so long as you are sanitary in the process.
Like the 2nd poster said, if it bothers you, do it.