I just got back into brewing and I have a pack of S-05 that says expires 2007. It has been refrigerated the whole time. Can I still use this or is it bad?
I dunno yeast is pretty hardy stuff. I would get an extra packet as a backup, and try rehydrating it on brew day. If it looks active when you rehydrate it, just try pitching it and see. You may get a bigger lag on an old packet, which maybe you don't want if you are going for a clean fermentation profile.
Although, if it has been stored at room temps and/or high temps then it's probably not too good at this point.
I had a pack from 08 that had been stored in the basement in about 65* temps. I just pitched it here a few weeks back, and about 10 minutes later I could smell the "bread" smell, which told me the yeast was alive and well. The beer fermented just fine.