Barrel Theory is a must-try and light rail makes it easy. A lot of local beer traders hang out there, kind of a headquarters. Tim is one of the brewers, he's super cool, everyone else who works there is great, just a great spot to hang out.
Town Hall is easy to get to from anywhere in downtown, it's a short Uber,train stop nearby, and you can bikeshare/walk depending on where you're staying. They'll probably have something barrel aged on and they make excellent hoppy stuff and also do solid pils, Marzen, helles, wee heavy, porters, etc.
Fulton and Modist over in the North Loop are also good close stops. Modist has a very good hazy IPA, Dreamyard, and everything else they do is interesting and different.
Fulton has solid hops, and some barrel aged stuff if you're lucky, and they do a few saison/farmhouse beers. They have a vintage bottle list, BA Libertine is kind of like a lighter barleywine, really good barrel character. They also have BA saisons/farmhouse on that list from what I remember.
Wild Mind is very good, not as close but worth a visit and pretty close to my house.
I think I'll be pretty free if you want to hang out.