I’ve tried various methods many times and finally settled on the PET bottle method. It’s quick, easy, clean, and I’ve never had a blowout while using it.
I put whatever I’m ‘injecting’ into the PET bottle (generally a brown PET 12 oz beer bottle), attach a carbonation cap, pressurize to about 10-12 psi, and connect a jumper line with GAS IN gray fittings on both ends.
When I attach the jumper line to the GAS IN post of the keg (be sure to have the bottle inverted before connecting), the fluid in the bottle flows immediately into the keg in less than a few seconds. No muss, no fuss.
As a follow up, I rinse the bottle with fresh water and a spritz of Star San, let the sanitizer and rinse water drain, and then put a few ounces of sterile water in the bottle. Reconnect the carb cap, pressurize, reconnect the jumper line to the bottle, invert the bottle, and connect the jumper to the GAS IN post of the keg.
The rinse clears any remaining fluid that was being injected from GAS IN post. If you’ve ever mistakenly connected the wrong connector (beer out) to the wrong post (gas in), and experienced sticky beer residue in your gas post that resulted in loosing pressure in your keg, you’ll appreciate this final step.
As I said, this is the only method I use anymore, and it’s nearly foolproof, with me playing the leading role of “fool.” I’ve used the plastic syringe with Lure Lock connectors and nearly always had issues, some much messier than others. This PET bottle method is about as safe and secure as any I’ve tried.