It depends on what type of regulator you have. Most should have provisions for 2 guages.
The guage on the tank/high pressure side is useful but not as useful as some may think. CO2 will remain at a constant pressure until all the liquid CO2 is used up. It will then drop pressure fairly quickly. At our shop we are lucky to squeeze a full day out of our fountain machine on an air filled tank with no liquid CO2 left. We use a 20# tank.