Are you using an O2 tank or whisking it? If whisking, you should wait to pitch after aerating. And you also don't want to "mix" the yeast in, just sprinkle it either over the wort or a cup for rehydration. At the point of pitching the cells walls are not fully formed. Swirling the yeast around vigorously can do one of two things: 1) Let water into the cell too soon (before it has fully formed a cell wall to regulate movement of materials) and bring toxins with it, or 2) Whisk the yeast around too much and, due to the lack of a cell wall, "centrifuge" the cytoplasm (cytosol, organelles and proteins) out of some yeast. This will result in lower viability of your total yeast packet, thus lagtime and such.