They are menat for computers running 24/7 at fairly warm temps. You don't have to worry.
Mine has been runing for about 2 years. I have 2. One 40mm in the tower opening and one 4" fan near the kegerator "hump" to move the cold air around. The 4" is off. I was using it to move the air around but my power supply was a little lacking so I turned it off. The little 40mm moves enough air and cools the tower just fine.