I have a lot of friends in Seattle, and visit there once or twice a year. You might want to check out the Red Hook Brewery tour, I quite enjoyed it. Of course it included a tasting session of all their products, for the price of a $1.00 glass. (Which is yours to keep.)
When I took the tour, the brewery was in the university district, but I believe it's moved since then. Should be easy to find though.