No experience with Galena or El dorado.
My experience with Mosaic and simcoe is that the will both contribute some fruitiness but also some dankness, which may or may not be to your liking (some love that, some, like me, could take it or leave it (usually leave it)).
My experience with Citra and Azacca in NEIPA is fantastic.
IMHO, stick with no more than 4 hops varieties, and I think 2-3 is better. My reasoning is that let's say you love it but it has one element you don't care for. With so many varieties, you'll never be able to troubleshoot and identify the responsible party.
Two batches ago I did one with Mosaic and simcoe early, And all Citra and Galaxy in the dry hop. It was amazing, except for a slight dank hint that I didn't want (I was going for a pure tropical fruit bomb). I figured the Mosaic or simcoe or both were responsible, so my most recent batch was all Azacca, Citra, and Galaxy.
Pure fruit juice. No dankness.
Some folks thing Galaxy can be overpowering, but that's not my experience.
I will use that combo again or just drop back to Citra/Galaxy w/o the Mosaic and Simcoe.