I know this is an old post, but not many people have good experience with S-33 for some reason. It's actually my house yeast I use to ferment most of my recipes. My Copperhead Ale I (American Amber Ale) has had the best results with using S-33, I also made a Cream Ale using S-33 with amazing results as well.
It is a low attenuator unfortunately so you have to plan according to with the recipe. It's a very violent fermenter as well, I sustain and propagate my yeasts so I've only needed one slat so far of S-33. It has mutated, but I really like where it's mutated to. It has attenuated better since the first couple of generations.
Here's a list of beers I've made with great results using S-33
Stout
Cream Ale
American Amber Ale
American Wheat
Pumpkin Wheat Ale
English Pale Ale
American Brown Ale
As you can see it is very versatile, but then again everyone may not have the same results. I also recommend blending this yeast with 1056 in a APA. I'm still working on the fermentation schedule of blending for great results. However this yeast is such a violent and quick fermenter it kinda makes the 1056 short on food. I'm hoping my next batch I got the schedule right!