Well, there is evidence that antioxidants are prevalent in red wines. That would lead me to believe that fermentation will not hurt the beneficial antioxidants in blueberries.
I have no science to back this up, though.
That said, acid is a good idea in your recipe. The blueberry melomel I made really needed acid.
Be that as it may, it seems that the important bit i.e. the "good" bit, in red wines are flavinols. They're actually present on the seeds - but you can get reds with good amounts and reds with few.
It's about skin/seed contact time in the ferment a.k.a. to maximise that, you'd have to be thinking of a rohapect type enzyme, then punching down the cap daily, probably until the ferment is complete and the skins/seeds have sunk in primary.
Then most likely, if the yeast has any room for higher alcohol tolerance, stabilise, then more of the enzyme and the fruit to secondary.
If carboys are to be used somewhere in the process, it'd be better to make it as primary in a bucket, then once you know that the brew either can't or won't start to referment with the addition of further fermentable sugars, they can be added to a carboy, but it would still need more of the enzyme and then a gentle shake each day to keep the top fruit moist, and then it up to the maker whether to do the "let them sink" thing with the secondary.
Any acids etc shouldn't be added until the end, and for best results, complimentary acids and even then, I wouldn't add any until after any sweetening was done i.e. just to balance any residual sugars.........