No not really. As I understand it the conventional wisdom was you needed some sugars in the boil for proper hop utilization, but the Brewing network guys did an experiment where they seemed to debunk that idea by boiling hops in plain water. Most folks don't boil plain water though. If you have some steeping grains you can just do your boil with the steeping water and add all your extract at the end, or if no steeping grains maybe boil with a small portion of extract (like 1/4 to 1/3) then add the rest at the end.
Edit: my mistake, I meant to say the Brewing radio guys