I think a lot of the effects of MSG were overblown like the aluminum pot/Alzheimer connection.
I used to grew jalapenos too but it was discouraging because I'd go to the farmers' market and they were practically giving huge, plump ones away. So I just bought them. Plus, my soil is so acidic that I never could get the mellow taste in any peppers I wanted.
As far as mole, I have zero problems using it (depending on type). It's as southwest as southwest can be. Good stuff.
Penderys is fantastic. The amount of chili powders/peppers/spices they offer is almost as varied as grain selection at a homebrew store. I use them exclusively (helps that the place is literally two blocks from my wife's lab). Think of chili powders as malted barley, sure you could grow it yourself and modify/kiln it, but it's usually best left to those who excel at it.
I use their powders in my recipe with great results in my basic recipe. You can try it out if you want.
1# - top round steak
1# - bison sirloin (or chuck roast)
1# - venison backstrap
3 Tablespoons - Pendery's Top Hat Blend
3 Tablespoons - Pendery's Carol West Blend
3 Tablespoons - Pendery's San Antonio Red Blend
1.5 Tablespoons - Ground Cumin
1 Tablespoons - (cayenne pepper)
1.5 teaspoons minced garlic
1 large can diced tomatoes
1 - 8oz can tomato sauce
3 whole jalepenos
1 half small diced onion
Salt to taste
bacon fat for browning meat
Pulse chop all meat together in food processor.
Brown in bacon fat.
Simmer @ 45min with Top Hat powder, diced tomatoes and sauce, bringing water level to top of meat.
At end of first simmer, add Carol West blend, cumin and cayenne pepper. Add water as needed and simmer for 45 minutes.
Last dump add garlic, salt, whole peppers, onion, and San Antonio Red and simmer for 20 min.
That's pretty much it but sometimes I play around with the heat and meat selection.