Depends on many things like how vigorously you are stirring, how finely divided the bubbles are on exiting the stone, the flow rate through the stone, the volume of the water. I've found that with pure O2, a sintered stainless stone and a flow rate of about 0.5 LPM that 3 - 5 gal of wort can be brought to about 20 mg/L in about 3 min.