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Will beginning with a lower initial gravity of the starter wort have any advantage by shortening the time to reach catabolic repression? What would be optimal starting gravity if continuously aerating with an aggressive whirlpool were employed?In fact, because the solution at this point will contain greater than 0.4% glucose, aerobic metabolism will initially be inhibited. Only after the glucose content of the solution has been reduced below 0.4% will the catabolic repression of the Crabtree Effect be removed. At that point, if there is still oxygen left in solution, then the yeast WILL employ aerobic respiration and will reproduce quite efficiently until the oxygen is used up.