Yes, there are *some* justifications for them. One case where it makes a lot of sense is if you're building a small pilot brewery for a larger commercial setup. No reason to mix and match connection types.
It's more likely I'm asked if there are any reason to go with TC on every port of every vessel for a 10 gallon homebrew setup and my answer is generally no. It's an even bigger no if there are any other factors like budget. If you've got a welded 1/2" coupling as a drain port, you'd need a TC adapter, then TC valve, then a TC to hose barb. Add two clamps and gaskets. Even if you go with the cheapest China seller on Ebay you're over $110 just for just one of those sets. In NPT/camlock it's $36.
Budget aside, 10 gallon pots look obnoxious with TC hardware cantilevered off the sides, especially with it's an HLT with some 5 ports.