20 gallon batch?

Wondering if there are any problems with doing a large volume batch. I'd like to do enough for 4-5 kegs at one time and since I only boil 2 gallons per batch (using extract and partial grain) I have the equipment to do it. 15 gallon pot, turkey fryer burner and all the primary's, secondarys etc. I just think it would be easier to clean/sanitize everything all at once and be done with it. I just haven't tried it yet. Has anyone done this? If so what should I be concerned about?

no real problems except for scale

we do 50 gallons with no probs

Thanks
Looks like I just need to find a couple beers that I want to drink alot of!