No, but if you want to sell beer that you make, you have to get a small beer producer's license, a brewer's bond ($1000 if your state is cheap) and pay rent on a space that is not your home. Which makes any beer you produce there not home brew. You cannot, in any state, make beer you brewed in your home.
Hope you're lawyered up if you want to become a professional brewer- and that's what you'll be. If I play basketball, I'm a basketball player, but if someone pays me to play basketball for them, I'm a professional basketball player. You'd be a professional brewer with a licensed brewery, not a homebrewer.
Even if you stick to 5 gallon batches and plan to lose money for the rest of your life, you still need to rent a space, apply for and be granted a fictitious business name, get a business license with your city or county, apply for and be granted your state and federal small brewer's licenses, brewer's bond, various insurances (liquor liability at a minimum, if you're smart), get your rented space inspected regularly by the ABC, TTB, OSHA, and DOH if your county wants in on the action. Then you need to pay rent, utilities, and upkeep on a brewery you can't legally operate during the 90 days it will take to get your licenses, if every single thing you own and built was up to code and you are familiar with the phone book that is alcohol law.
You can, in some very special unincorporated areas, get a special use permit to re-zone a separate building on property you own (eg a garage) but you don't get to skip out on all the lovely licensing and inspections. Even that's if your community wants another brewery. If they don't, you get to go to all sorts of special hearings before anyone will even think about giving you a license to brew beer.
Once you've succeeded with all the easy stuff, then you have to meticulously record every millileter of beer you ever produce and make sure that every single person who was involved in the ratification of your brewery as a commercial enterprise "gets theirs." If you don't dot a T or cross an I, the Fed (or whoever you accidentally shorted) will go after you for everything you've got, regardless of if your'e a sole proprietor, an LLC, or a Corporation (gasp!).
Not trying to be discouraging, although that's the way it sounds, that's just reality. Ask me how I know.