The posts just need to be on hand-tight. You don't want to strip the threads. The posts were on awful tight on the kegs I have when I bought them, but they were gunked up with soda syrup.
If this is a used keg, you're going to want to clean the hell out of that thing. Rinse it out good with hot water, and then put some Oxyclean solution or some other oxygen based cleaner (Straight-A, PBW, etc.) in it and let it soak. Do the same with the parts. After soaking, rinse everything off good with hot water. You may also want to take a Scotchbrite pad and some Bar Keeper's Friend and scrub down the outside to make it look better. If it has any rust spots inside you will want to scrub that with Bar Keepers Friend as well. If you scrub the keg, let it sit for a few days so that the metal will reform a protective layer over the scrubbed areas.
You will want to replace all of the O-rings, and probably the poppets as well.