Staying somewhere in east side would put you within walking or short rideshare fares to Rainey (Craft Pride, Bangers and all the various bars there), Hops and Grain, and Zilker. Could even throw in Live Oak if you wanted. Somewhere around South Congress/South Lamar would also be ok (you could hit ABGB and Pinthouse). If you're up for even more breweries, there's brewery/party tour buses who can sort a whole itinerary out. Jester King doesn't allow party buses FYI.
And you'll inevitably end up on dirty 6th, somehow.
Other than brewery stuff, the most common suggestion I hear is water activities. You do have enough people to where you could consider renting out your own boat for a lake. May even be nice enough weather to take a swim at Barton, go tubing, or paddle boarding/kayaking but honestly it's a crapshoot. Top Golf? If you're into video games/pinball, load up on good booze and Pinballz is BYOB.