I grow 9 varieties in South Central PA. Centennial and Chinook are my primary producers, both of which were harvested multiple times already(both 2nd year plants.) SAAZ grew well for a first year, and so did my Hallertau so yes you can grow noble hops. Both produced just by smaller amounts. I also grow Fuggle, EKG, Northern Brewer(was finicky and produced a little but later in the season), Mt Hood which did well this year(nothing last year.) I also have a Cascade plant and even though Cascade is found in the wild here, mine had issues both years now. I would go from what your tastes are for beer you like and go from there. Most hops will do well in PA.
beerloaf