Definitely! LoneRider, Carolina Brewing Company, Big Boss, and Aviator are all good. CBC is right next to my house and is REALLY popular. Usually about 150/week. Perhaps because of the free beer. Big Boss is nice too, but for some reason I've never been a huge fan of their beer.
Are you new in the area?
EDIT: Just noticed you said NC in general and I just gave you Raleigh. Let me know what part and I point you to some places. There is LOTS of good beer in NC.