One of the oxebar kegs? If so, sure with a few extra steps. You can run a line from the liquid out, stepping up a few times to get to the 1/2 inch size you’d have on a hand pump. Floating dip tube works just fine.
You’ll need some way to replace volume as you draw out your beer - I’d suggest a proper cask breather or I’ve seen that people use a propane regulator which seems to work fine. Alternatively you could pulse the keg with CO2 while you draw off, but you’d want the pressure low enough that it won’t push the beer up through your beer engine but high enough to replace the drawn off volume.