I have no experience with duotight but we used to use push to generic connect fittings extensively at work. I learned two main things. First, make sure the hose is fully seated, a lot of fittings have a "false bottom" feeling and a lot of new users tend to not fully seat the tube. Second, the hoses tend to get scratched up from inserting and removing them and this will lead to leaks eventually. If you're disconnecting hoses regularly you may need to trim off the very end of the hose to get a smooth finish for the oring to make a proper seal.
Also they tend to not like a lot of sideways force on the tubing, in other words coming out and straight into a tight bend. Though this is exactly what the duotight fittings advertise they are good for.