I'd be very cautious using a vacuum pump unless you know that the vessel you're using it on can withstand it. For example, a commercial bottling line will usually use a vacuum while purging bottles where canning lines cannot without collapsing the cans. Many conical fermenters (unitank and otherwise) cannot handle much for negative pressure despite being able to handle lots of positive pressure.
If you wanna build something and try it with a vacuum pump, safely test it first and understand the chance to collapse it is there. If you're buying something, I'd ask. If they don't know the answer, see above.