Some will say unless you can crop the yeast off the fermentation you may get some flavor issues, very much dependant on the overall conditons. You can start and go all the way with a top pressure, but it needs to be controlled, not just a Corney blow off! I think bad things may happen. If you fit a ball lock connector with a small air regulator in reverse fitted with a 0-60psi guage on the in side of the keg you will be in control. Look up your PVT=C table and choose your pressure based on your target CO2, and ferm temp. Should work just fine. Thats how we did it in the brewery, with a small trim just prior to bottling if necessary.
I have had flavor problems with some yeasts, probably because I have over pitched and over feed and not been able to off crop yeast. Its a one shot deal, I think if you get the recipe dialed in its a great way to have repeatability, problem is most of us are tweaking things all the time.