All very good suggestions. I personally think the food at Widmer is excellent and the beers are good as well. Hopworks is a great place but a smashing success and a bit hard to get into sometimes. Rogue, Dechutes, Bridgeport, Rock Bottom, and Tugboat are all brewpubs in Downtown (Full Sail only has a brewery but not a pub in Downtown). Henry's has so many taps it is hard not to find something good. On the East side (where your hotel is located) are Widmer, Lucky Lab, Roots, and Hopworks Urban Brewery (HUB) brewpubs. Of course if you want to expand your list to great pubs, the Horse Brass, Green Dragon, and the Concordia Ale house are all worth a trip. You have a lot of choices within the inner city. McMinimums pubs are all over the place (20-30 of them). I know, kind of hard to choose. For sure use MAX. I think the first stop on the airport line from your hotel is Widmer (Interstate).
Best