I did this:
Plain distilled water at 60F and took a reading with my floating hydrometer to verify it was reading 1.000 and it was. I then read the same DI water with my refractometer and it was slightly off zero so I set to read zero.
Made a small batch of wort (enough to float the hydrometer) by dissolving a few tablespoons of DME in some hot water making sure it was totally dissolved. Cooled to 60F and it read 1.055 with the floating hydrometer. Since I had confirmed it was at zero with DI water, I trusted this reading to be accurate. I read with refractometer and it was 1.057 so I adjusted the screw so it would read 1.055.
My experiences are that the floating hydrometer when checked as I did, is typically more accurate. The convenience of the refractometer is the allure, but with some calibrating, it is good to go. Post (or during) fermentation readings with your refractometer needs to use an online calculator but is really simple.