Hard to see but the underside looks like sucking insect damage. Can you see any spider mites, aphids, gnats? If the buds have not set you could try an organic insecticide. My pappy used to soak a bag of Bull Durham tobacco in a couple quarts of water to make something like sun tea, and spray the tea on the leaves (top and bottom) with a hand sprayer. Iron deficiency can cause leaf yellowing but this case seems beyond that.