My take is that it is as safe as commercial beer or any other commercially available consumable out there. It's not going to instantly kill you unless you intentionally poison it. Long term and substantial exposure to alcohol and other substance in beer, both home brew and commercial, may have adverse health effects on some.
Things like mycotoxins from the grain, BPA and endocrine disruptors from plastics, and lead in brass and other metal fittings are a concern to some people.
If you have a true concern for these things, I say, do your own research. I mean real research, not just seek out the opinions of people on the internet. You'll find some interesting debates on here, but you should seek the research done on these substance and draw your own conclusions.
Like I said, some have a real concern and strong opinions. Others, like me, don't. I don't feel I consume enough to have a significant impact on my health.