Huh? Not to be argumentative, but my experiences with PRTDs were quite different than yours. Like you, I designed and implemented DACs - for laboratories and manufacturing settings in situations where temperature knowledge was critical to our control processes.
The industry standard for platinum RTD's according to
DIN IEC-751 is Class A
or B, that is, a typical accuracy for Class A ±0.15°C at 0°C, and ±0.35°C at 100°C, with ±0.3°C at 0°C, and ±0.8°C at 100°C in a Class B setting. This is quite good when compared to the ±2.2°C of a standard Type J or K thermocouple. And as you state, the DFL - dead frakking linear.
You may recall accuracy:
Class A: Dt °C = ± ( 0.15 + 0.002 | t | )
Class B: Dt °C = ± ( 0.30 + 0.005 | t | )
where: | t | = absolute value of temperature in °C
As for two-wire versus four wire, the two wire setting is subsceptible to resistance changes in the lead wires and/or connections, whereas the resistor bridge in a four wire setting offsets and nulls that out. I never bothered with two wire setups, given the ease of implementing four-wire.
Another reason the PRTDs are well liked in industrial and laboratory conditions is that cycle to cycle differences normally cant be measured and are considered lumped into stability specifications. Further, you can typically you can count on the probes to be almost totally non-reactive. Some J and K thermos were pretty weak in that regard and were not long lasting. Not only that, they tend to require relatively constant calibration in my experience.