Which pups you looking at? Single coil? Or humbucker?
What type of music do you play, what kind of guitar?
I need a bridge humbucker. I have an older Kramer Focus EVH style into which I routed a neck pickup slot. I need to replace the bridge pickup which went into another guitar. I'll also need to decide how to wire it with coil taps, push/pull, etc.
I play mostly classic rock/metal style. EVH, Satriani, and any classic rock type thing. I'm hoping for a fairly decent range of tone and power, but that's basically what I want in this guitar. I'm planning on detuning for EVH songs.
At some point in the nearish future I want to build a guitar from mostly scratch. I'll probably try and find an inexpensive neck and maybe cut and rout my own body shape and a variety of electronic wirings. There are some interesting things you can put right into a guitar body these days.
Guitar Fetish has some low cost pickups I'm looking at. I've heard good things about them. Should be cheap enough that I can play with them without breaking the bank.