My very limited experience, if your water is "in the range" on minerals, then you are good. I HAVE seen and tasted the difference between water closer to Pilsen levels vs Burton on Trent levels. It is pretty clear.
That said, minor adjustments, I honestly believe you will not really taste a difference.
With gypsum I've tried several experiments now in relatively similar beers, I can't notice a difference trying two beers side by side until I hit roughly zero vs 1tsp in a 3 gallon batch. At THAT point, The hopiness does seem just slightly sharper and the beer just slightly drier. At double that level, the effect is a bit more pronounced and not pleasant. A slight adjustment, I don't think I'd notice. I've tried a couple of experiments with salt and epsom, and my experiences were "I didn't notice" or "it was unpleasant" depending on the level.
Other people may be more sensitive, no I wasn't doing a heck of a lot of balancing and slight tweaking. I think you can 'punch it up' a little by adjusting minerals, but IMHO you are either making a BAD beer, or at best, you are improving the beer a very, very slight amount. Which, obviously I want the best beer I can, so it can be worth while to do if you don't mind, but it isn't going to make a good beer great, or a bad beer good. It might make an 8.9 beer a 9.0
Yeah, I do tend to add a little gypsum to most of my APA, IPA and DIPAs, because at the right level, it does tend to enhance the bitterness in a nice way if I go gentle with it. It might (to me) make that 8.9 IPA a 9.0 to me, so why not for little cost or effort (since I've already played with it). I just don't have a lot of desire to futz with other minerals much, because having played with them some, it either made beer worse, or at best didn't impove things more than a slight bit, and I am too lazy right now to research beer styles and try to put together a mineral addition sheet for that specific style, futz with 3-5 different minerals, etc., etc.
Just like with Pilsners, I notice a slight difference when using 2/3rds RO/distilled water mixed with 1/3rd tap water, so I tend to do that. It doesn't punch a pilsner up to a 10 from an 8, it might make an 8 and 8.1. But it is easy to remember and do, so I do it.