B4B: From what Palmer says, you'll definitely know the difference. Normal healthy yeast sludge doesn't usually smell all that great, but it's not "blech!" nastified. When autolysis sets in, he says it is so bad that it may make you gag. Like a bushel of really rotten eggs. I'll take his word for it, and try not to recreate it on my own.
I dumped a 4" cake of Pacman yesterday. I too had been saving it in a sealed carboy for 2 weeks, too damned lazy to clean it and put it into jars. Plus, I had fermented my Burninator barleywine with it, which was made with star anise...and that star anise leeches into everything, including the cake. Plus, I had already gotten like 4 brews out of the Pacman, so...what the hell. Probably started mutating by now anyway.