For all my bottle harvests I've followed a reommendation for 1/2 cup water to 1/2 oz DME with 1/8 tsp yeast nutrient (generally used for wines) , allow to ferment out for a couple days then add a 1 cup water mixed with 1 oz DME and 1/4 tsp nutrient, allow to ferment out for a couple days then add one last addition of 1 cup water, 1 oz DME and 1/4 tsp nutrient and allow to ferment out. I have no idea if this is optimal but I've had great results and wound up with a lot of yeast growth from it.