About six months ago, when I first started looking into brewing I spent a lot of time researching this, as I was on a very tight budget. The two main areas of concern were:
Oxygenation of the wort: After mulling over all the research I determined that this would only be a problem if you are aging for an extended period of time. What is an extended period of time? I have brewed two batch and I use these bottles for both primary and secondary. Primary has been out to 10 days while secondary has been out to 4 weeks; both batches turned out to be good beers. So, I would bet that for most beers you would be fine but if 3+months of aging is required who knows.
Second issue had to do with the glues used to make these bottles; I look at life this way; there are so many possibly harmful things we eat, drink and breathe that the "potential" leaching of carcinogens is way down on the fright list. One would think if there is leaching of carcinogens into the beer there would be off flavors and I have not experienced that.
The upside to these bottles; very cheap and light. This is all from a newbe/laymans point of view do your research and make your best decision and relax. Cheers!!