if I remember correctly from my younger partying days, having a beer while on psychedelics wasn't a big deal.
i'm not saying it wouldn't work at all, and i agree that the boilerplate risk blurb may be overblown but I also have my doubts that the additions would add anything positive to the beer in terms of flavor, etc. - properties that could be perceived independently of the mental effects - and taking the drugs separately works and is much simpler and cheaper and safer. in my opinion...
Dry hopping with pot is an interesting idea. Though I'd need some convincing to dump an ounce of high quality weed into my beer
Solution: smaller batches. my project for this summer is to run a few single hop IPAs this summer to illustrate the differences between the hops for a tasting panel. For each batch, I plan to take the first half of the batch from primary and force carb straightaway for bottling for the hops tasting panel, then for the second half of the batch I will try some experimentation in secondary; dry hopping, chile adds, filtration, etc. One of these sub-batches could include dry-hemping, and in this case, if I'm dry-hemping with less than a whole batch, I wouldn't be using a whole ounce. plus this would allow to use different varieties; i imagine that hazes and skunks would be better for certain beers and kushes would be better for others. If I had four growlers and four different kinds of kind, I could mix and match to see what works best, and how much of an addition would be appropriate. Also, maybe kif or hash works better, who knows. This sort of experimentation could get expensive quick, even where I live, but I am fairly certain that the price is only going down, especially for anyone that can legally produce their own supply.
One note; in the past I had a similar notion, and took some trim off a grower friend's hands, basically just stuffed a bagfull in a corny and racked some high test beer on it. Found out the hard way that the chlorophyll thing really is an issue, and one must be very diligent to make sure there's no foliar feeding residue or other contamination.
Another note: i acknowledge that mescal is not mescaline, thread title is misleading. Nothing illegal about mescal beer, as far as i know, and actually, being a tequila fan, i would imagine this could be pretty good. not going there today though.
In the event this thread gets shut down by those who choose to assess the legal risks of such discussion more conservatively (as is their right), feel free to PM me and we can take it offlist.