I was going to call my ESB I'm bottling this coming weekend something else originally, but this just seemed too perfect. Dr. Greg House is a bitter, bitter man. And, hey, Hugh Laurie is British, so that fits too.
Nothing. Lupus is a disease that becomes a kind of running joke in House since it gets thrown out as a potential cause for patients' conditions in several episodes. It never ends up being lupus, and at one point after it is suggested Dr. House just says, "It's never lupus.".