The tolerance for most of the commonly available infra-red thermometers that I have seen is only +/- 2% IIRC. I think they are probably somewhat closer than that in actual use, but generally they aren't all that accurate.
Here's a spec sheet from Omega listing some of their models and the accuracies:
http://www.omega.com/temperature/pdf/SEL_GUIDE_IR.pdf
Even the relatively expensive ones aren't all that accurate. I have a moderately priced one and it's handy for quick checks of the fermenters and the output of my chiller, but not of much use for anything else brewing related. Steam and vapor coming off of the mash will interfere with the readings and they only read surface temperature. Reflective surfaces can also interfere with them.