I've been making muscadine wine for a few years. My very first year was a complete bust so I don't really count that year. I always wash and then freeze until I have enough to make 2 gallons of wine. Each year I increase the amount of muscadines I crush and back off on the water I add. 2 years ago, I used EC-1118 yeast. Last year I used 71B-1122. I haven't decided which yeast I'll use this year. Now that my 1118 batch has been aging for 2 years, I like the taste but wish I had used more muscadines and less water. I think last year's batch will taste really good this time next year. As you can see, I'm still in the experimental mode with finding the perfect blend of muscadines to water ratio.
BTW, I grow my own muscadines: Southland, Black Jumbo, and Noble. I only have 4 vines total. I just mix them all together to get the amount I need.