I will tell you as a hiring manager I look at a few things. If you don't pass those, I do't even read the rest of the resume. i know these are most likely un-PC, but this is the best way i have found to comb through 500+ resumes per posting.
I look at:
email address... keep it simple, like your name. Nothing stupid. like XXXBoi6969
Physical Address - I like local. If you are out of town, put on there you are looking for a job in XXXX region and will pay for relocation. That would make me keep reading.
College/University - If you go to a real school, I keep reading. U of Pheonix and Devry doesn't pass the test. If not, talk up your experience in the field you are applying for. I will often times substitute learning with real experience that can't be taught in school.
For first time job seekers, I will then go straight to extra-curriculars. If you deliver pizza in college, I get it, i don't need to know about how you were a diligent order taker and exceeded delivery times. That doesn't mean **** in the real world. I look for Fraternity/Sorority or other clubs and organizations. I then look for leadership positions within those. My thought is if your peers elect you to leadership, they must think highly of you and so will I.
Hope that helps. Good luck. Keep in mind 99% of the world hates their first job/boss. If you are going with accounting, I would recommend you go with one of the Big 4 and work your way out of them after you make Senior. If that's not you, look for something quickly in the arena of what you want to do. Gaps in employment are another red flag for me.