There’s absolutely a difference in the “type” of bitterness. It’s not purely a IBU factor.
A recent craftbeer and brewing podcast with the headbrewer from Slice talked about west coast IPA and how if he used classic C hood, his bittering rate was closer to 40ish IBUs, while with more modern fruitier hops, he was higher at 50-60. The classic hop bitterness was a bit sharper and more aggressive, even at lower IBUs.
My last batch, I used cascade in the boil because I was out of my lager hops, and there’s a more resiny bitterness. Generally, my preference is to use a classic bittering hop for the first 20IBU addition. I love summit, but warrior or magnum would be good choices. Plus, you generally only need about .25oz/7g. Then later in the boil use the “lager” hops. Sterling is like a more citrusy saaz, saphir is super delicate and floral. Pinthouse brewing here in Texas which won a GABF silver for their version of Timbo has been using hallertau Blanc for their book additions. I really think any classic lager hops or their American derivatives like mt hood, liberty, vanguard, etc would work. It could also be a way to use some of the modern German varieties like Blanc, Huell melon, mandarina, or Callista to have a blend of classic lager character with modern flavors that will work well with the big ipa dry hop. And with using those in the 30min and whirlpool, you’re getting a more delicate, finer bitterness addition.