Depends on what you want for an end product. Do you want sweet, dry or semi sec? Do you want enhanced mouthfeel or a softer melomel? There are a lot of things that different yeast strains can do, you should choose your yeast like you would choose a tool. What qualities do you want in your end product? What type of honey, what type of fruit, how much, etc...
More info will help.
Regards, GF.