Originally Posted by hbhudy
How many times can you "reuse" a yeast cake? Would it be OK to split the yeast cake after the 2nd usage?
IIRC, its usually safe up to 10 generations, you may start to get mutations thereafter.
I wouldn't use a whole cake tho, its far more yeast than you need. around 1 cup of slurry is good for most ales - use mrmalty for exact figures