You are asking a very big question there. By the fact you are in the mid-atlantic doesn't mean much. Apples are hardy to way further north. We have quite the apple industry in Vermont and can grow just about any cold hardy variety.
As far as personal choices, I personally have 5 trees and will be grafting on more variety to my current trees. I can't decide so I keep adding more variety.
Pick and choose, can't go wrong. My personal thought is to check local orchards and don't get anything they have (Northern Spy for me). My current trees are Golden and Roxburry Russets, Calville Blanc, Cox orange pippen, winesap. I plan on grafting Sweet alford, Esopus Spitzenburg and Wickson Crab (and probably another variety or two). I also have a grafting of Yarlington Mill. I also have a nice large crab which will hopefully be a nice polinator.