Thanks for all the input. We went to Goose Island, Hopleaf, and The Map Room. All fantastic bars that blew us away, especially Goose Island, which I would have stayed at much longer if we weren't gonna walk 3 miles back to the hotel!
Got to tour Miller which was cool but pretty touristy, which was to be expected. Also took a detour to Bell's and had lunch. Soooo awesome. My wifes all about the road trips and stopping at breweries now so I think were going to head west next time